Grapefruit may cause adverse effects if taken with some medicine

Grapefruit may cause adverse effects if taken with some medication

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By STEPHANIE BEECKEN
6 News Reporter

KNOXVILLE (WATE) - Doctors say the number of prescription drugs with potentially deadly interactions with grapefruit juice is growing.

The interaction was discovered more than two decades ago, but now there are nearly 90 known drugs on the list, 43 of which can cause serious problems, including sudden death, when taken with grapefruit.

Leah Schumacher, a registered dietician at the University of Tennessee Medical Center, says the grapefruit juice increases how well the body absorbs certain drugs.

So if the drug is taken with grapefruit or grapefruit juice the body will absorb more than needed, sometimes causing adverse reactions.

Schumacher says there are now more drugs made that interact with grapefruit juice but that your pharmacist will put a label on your medication if it does.

"Being on one of these drugs doesn't mean that you can't ever have grapefruit or grapefruit juice in your diet, it just means you shouldn't take the medication with a meal that includes grapefruit juice. You really need about six hours between taking the medication and eating a grapefruit or drinking grapefruit juice," said Schumacher.

If you have concerns about your medication possibly interacting with grapefruit juice ask your pharmacist.

For more information, visit the National Institutes of Health release.

Below is the full list of prescriptions that could interact with grapefruit:

Alfentanil(oral)

Amiodarone

Apixaban

Atorvastatin

Buspirone

Clopidogrel

Crizotinib

Cyclosporine

Darifenacin

Dasatinib

Dextromethorphan

Domperidone

Dronedarone

Eplerenone

Erlotinib

Erythromycin

Everolimus

Felodipine

Fentanyl (oral)
Fesoterodine

Halofantrine

Ketamine(oral)

Latatinib

Lovastatin

Lurasidone

Maraviroc

Nifedipine

Nilotinib

Oxycodone

Pazopanib

Pimozide

Primaquine

Quinine

Quetiapine

Quinidine

Rilpivirine

Rivaroxaban

Silodosiz
Simvastatin

Sirolimus

Solifenacin

Sunitinib

Tacrolimus

Tamsulosin

Ticagrelor

Triazolam

Vandetanib

Venurafenib

Verapamil

Ziprasidone

(Source: ABC News)

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