LENOIR CITY, Tenn. (WATE) — Three people have been injured after a semi tractor-trailer hit a vehicle then overturned Sunday on I-40 in Loudon County, according to the Loudon County Sheriff’s Office spokesperson Zac Frye.

According to the TDOT SmartWay map, the semi overturned around 4:32 p.m. on I-40 eastbound near Buttermilk Road. According to LCSO, the wreck also involved a possible fuel spill.

According to Frye, the semi hit a car with two people in it and then overturned. After the crash, the TDOT camera showed cars stopping in the area with the semi on its side blocking the highway.

The two people, one female and one juvenile male, in the vehicle were injured in the crash. Both were taken to a hospital. The driver of the semi has been airlifted by UT LifeStar to the UT Medical Center.

The Tennessee Highway Patrol worked the scene with assistance from LCSO, Frye said. Heavy traffic was expected since the lanes were blocked.

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According to TDOT spokesperson Mark Nagi, all cars stuck in traffic were cleared around 6:55 p.m. The cargo in the semi was carrying 42,000 pounds of frozen lasagna.

THP is currently investigating.